I also keep my boat in the dunes. used to be a trailer boat but now I got a bigger one in the water (now I miss the trailer boat...). Here are my tips for whatever they're worth:
1. One spot and two spot are super fun. Small wax wings, small live sardines, and some cut up chum go a long way. Good spot for mackerel, bonito, barracuda, and some sheepshead, etc.
2. Catalina pro move. Start at the east side and try and leave from the west (or more West than where you started) because of swell direction.
3. Sometimes it's better to stay more parallel to the swell, and then run up the island, on the Catalina runs to the west side.
4. If it's windy in the dunes, it's probably windy on the water.
5. Out rigs and muscle farm aren't far. Neither are the Long Beach spots and the swell is a good direction home from there.
6. Your boat is the perfect size to park the SOL for drinks.
7. Harbor patrol loves to tag boats for going too fast at the harbor mouth
8. The PCH bridge is a good spot for halibut and bass. Close to dunes too.
9. Get an EPIRB or PLB. Always do a radio check on your way out. Your chances of surviving an in-the-water ditching scenario, like a fire, just went up exponentially.
10. Carry a bass rod even if you're fishing for big stuff.
11. 14-mile bank is an easy run from where Newport and is an easily accessible offshore spot. An easy day is 14 mile bank to the one and two spots inshore. Real easy run.
12. Buoy weather is your friend.
13. The first 10 miles from Newport to Catalina suck a lot of the time.
14. The entire drive to Catalina sucks if you leave at 3pm. You'll just take it on the chin, but sometimes it's worth it.
15. Leopard sharks are fun to catch.
16. If the wind picks up at Cat while you're there, don't be afraid to spend the night there. Some good restaraunts and there are public showers you can use to freshen up.
17. Send a Glympse message to someone you know before you make a Cat run, especially at night or 3pm (see above). You should have cell service the entire way.
18. Bad cell service on the backside of Catalina (if any).
19. There are now a t mobile and verizon tower near the Navy base on San Clemente.
20. Know where the MPAs are.
21. Finally, fish and game sit at the dunes launch ramp. So don't do anything illegal like small lobsters or put of season rockfish. Also, border patrol sits there. So dont smuggle people or drugs.